A Randomised Trial of Timing to Restart Direct Oral Anticoagulants after Traumatic Intracranial Haemorrhage

Research summary

The main purpose of the trial is to determine when the most beneficial time for people to start or restart a DOAC after their head injury is. People will be asked to start the medication either 1 week or 4 weeks after their head injury. This will be randomly assigned by a computer. They will then be followed closely for 12 weeks and any major bleeding events or a blood clots (thrombotic events) such as a stroke or heart attack will be recorded. The study will also look at the person’s overall quality of life,how they recover physically,the number of people who die,the costs of the treatment,and the attitudes of people and their caregivers to starting or restarting a DOAC.

Principal Investigator

Dr vishakha prasad

Contact us

Email: emergency.research@oxnet.nhs.uk

IRAS number

1008878