Hypertension management in Young Adults Personalised by Echocardiography and Clinical Outcome

Research summary

The aim of our study is to personalise management of high blood pressure for young adults between the ages of 18 to 40 years old. In the UK, at least 1 in 17 adults below the age of 40 have high blood pressure. Controlling the blood pressure in young adults can be a challenge for doctors because information on the management of high blood pressure is mainly obtained from older people. To overcome this challenge, we will study clinical data, including blood pressure measurements and treatment plans in young adults, and will link them with the findings of clinical investigations (in particular imaging scans of the heart). We hope that this study will provide us with a better understanding of how to prevent heart abnormalities and control high blood pressure in young adults. We will be inviting 750 patients referred to Hypertension clinics within England, and aged between 18-40 years old to take part in the study. 250 participants will be recruited prospectively during the hypertension clinic, where a full set of data will be collected from each participant as part of their standard hypertension clinical service. An additional echocardiography (ultrasound heart imaging) scan will be performed for this cohort by the study team, if the scan has not been performed as a part of the clinical care service. 500 participants will be recruited retrospectively, and no additional echocardiography scan will be required for them. All Participants will be followed up for 10 years post enrolment to monitor their blood pressure levels, and their response to their treatment plan. The study is funded by the NIHR Biomedical Research Centre, Saudi Arabian Cultural Bureau, and Cardiovascular Clinical Research Facility (CCRF).

Principal Investigator

Prof Paul Leeson

Contact us

Email: cvm_nurses@cardiov.ox.ac.uk

IRAS number

247606