Investigation of the genetic and molecular pathogenesis of primary biliary cirrhosis. Protocol Amendment 3, dated 05 March 2008. Substantial Amendment 10 dated 09Dec2010

Research summary

The PBC Genetics Study is a national effort to establish a PBC DNA collection consisting of DNA samples from approximately 5000 patients with PBC. The DNA collection has already been used for a genome-wide association study (GWAS) of PBC. The next major analysis will be a genome wide association study of response to Ursodeoxycholic acid (UDCA).

Principal Investigator

Dr Emma Culver

Contact us

Email: ouh-tr.ctfresearch@nhs.net

IRAS number

32929