Cancer and neoplasms

ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study (ACTION)

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Reproductive health and childbirth

A Phase 3 Randomized, Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN) (Azalea)

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Metabolic and Endocrine

The Oxford BioBank [RENEWAL 2023]

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Risk Stratification of Interstitial Lung Abnormalities using Hyperpolarised Xenon MRI and blood biomarkers

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MyeloFiT: Myeloproliferative Neoplasms – Imaging-based assessment of Fibrosis and Thrombosis Risk (MyeloFiT)

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Oxford Genetic Frontotemporal Dementia Initiative 3 (GENFI)

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Interrogating immune- tumour interactions within the central nervous system

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A phase 1 study to assess the safety and immunogenicity of R21/Matrix-MTM administered in an escalating dose, multi-prime vaccination schedule in healthy adults (VAC096)

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Oral and Gastrointestinal

A Phase 3, Multicenter, Randomized, Platform Study of p19 Inhibition of the IL-23Pathway to Establish Efficacy in Pediatric Crohn’s Disease (MACARONI-23)

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A Long-term, Single-Arm, Open-label, Multicenter Trial to Evaluate Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis

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