Cancer and neoplasms

An Open-Label, First in Human, Phase 1/2 Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of the CTPS1 Inhibitor STP938 in Adult Subjects with Relapsed/Refractory B-Cell and T-Cell Lymphomas

GO TO STUDY

Cardiovascular

Global Clinical Study of Renal Denervation with the Symplicity Spyral Renal Denervation System in Subjects with Uncontrolled Hypertension (SPYRAL AFFIRM)

GO TO STUDY

Infection

D9185C00001, A Phase III, Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Tozorakimab (MEDI3506) in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen (TILIA)

GO TO STUDY

Cancer and neoplasms

An Exploratory Phase 1b/2a Multicenter, Open-Label, Novel-Novel Combination Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of CC-92480 (BMS-986348) in Novel Therapeutic Combinations in Participants with Relapsed or Refractory Multiple Myeloma (CA057003)

GO TO STUDY

A Window in the Brain 2: Novel quantitative seizure detection tool for paediatric critical care. A multi-centre feasibility study

GO TO STUDY

Extended Patient Diagnostic Imaging

GO TO STUDY

Cardiovascular

A Follow-Up, Open-Label, Research Evaluation of Sustained Treatment with Aficamten (CK-3773274) in Hypertrophic Cardiomyopathy (HCM) (FOREST)

GO TO STUDY

Using advanced magnetic resonance imaging to improve the understanding of cardiovascular disease

GO TO STUDY

Blood

A Long-Term Follow-Up Study in Subjects with Severe Hemophilia A Who Received BMN 270, an Adeno-Associated Virus Vector–Mediated Gene Transfer of Human Factor VIII in a Prior BioMarin Clinical Trial

GO TO STUDY

Cancer and neoplasms

Prospective Multicenter Confirmatory Clinical Evaluation of Novilase® Interstitial Laser Therapy for the Focal Destruction of Malignant Breast Tumours ≤15 mm (BR-003)

GO TO STUDY