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OUH STUDIES

Studies currently being run within Oxford University Hospitals NHS Foundation Trust.

Showing 531 - 540 of 764 studies

Cancer and neoplasms

A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC whose tumor PD-L1 status is considered negative (BNT327-05 (ROSETTA-Breast 01))

Metabolic and Endocrine

A Phase 2b, Randomised, Double-Blind, Placebo-Controlled, Parallel-Arm Dose Finding Study Evaluating the Efficacy and Safety of SAB-142 for Delaying the Progression of Type 1 Diabetes (T1D) in Patients with Stage 3 New Onset of Type 1 Diabetes (NOT1D). (SAB-142-201(SAFEGUARD))

Respiratory

A randomized, double-blind, placebo-controlled, parallel-group, multicenter study of the efficacy and safety of depemokimab adjunctive therapy in adult participants with COPD with type 2 inflammation characterized by an eosinophilic phenotype (ENDURA-2)

Cardiovascular

A Phase 2b/3, Adaptive, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Danicamtiv in Participants with Symptomatic Genetic and Familial Dilated Cardiomyopathy. | KINSHIP-DCM (DAN-301 (KINSHIP-DCM))

Congenital disorders

A Phase 2, Open-label, Basket Study Investigating the Safety and Efficacy of GTX-102 in Adult and Pediatric Subjects with Deletion- or Nondeletion-type Angelman Syndrome (GTX-102-CL210)

A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis (WIND-PSC Study) (WIND-PSC)

Metabolic and Endocrine

A Phase 3, Double-Blind, Randomized, Placebo-Controlled study of Baricitinib to delay Stage 3 Type 1 Diabetes in at-risk participants aged ≥1 to <36 years. (BARICADE-DELAY) (I4V-MC-JAJJ (BARICADE-DELAY))

Cardiovascular

Randomised EValuation of Therapies for microvAscuLar Injury in STEACS (REVITALISE)

Cardiovascular

A Global Phase 2b, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients with Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy – FORTITUDE-HCM (IMB101-010 (FORTITUDE-HCM))

Evaluation and simulated pilot deployment of “TrustedMDT-Copilot”: an agentic AI copilot providing decision support to Oncology multidisciplinary team meetings