Real-World Effectiveness of Belumosudil for the Treatment of Chronic Graft vs. Host Disease: A Non-interventional Retrospective Cohort Study Using Patient Medical Records (ROCKreal2)

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Cancer and neoplasms

A PHASE III, RANDOMIZED, OPEN-LABEL STUDY EVALUATING THE EFFICACY AND SAFETY OF DIVARASIB AND PEMBROLIZUMAB VERSUS PEMBROLIZUMAB AND PEMETREXED AND CARBOPLATIN OR CISPLATIN IN PATIENTS WITH PREVIOUSLY UNTREATED, KRAS G12C-MUTATED, ADVANCED OR METASTATIC NON-SQUAMOUS NON−SMALL CELL LUNG CANCER (KRASCENDO-2)

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Reproductive health and childbirth

A Phase 2, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of 2 doses of vipoglanstat in patients with moderate to severe endometriosis-related pain – the NOVA trial (The NOVA trial)

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Understanding adherence to weekly growth hormone treatment: A mixed-methods observational longitudinal study.

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Oral and Gastrointestinal

A Phase IIb, Multicenter, Double-Blind, Placebo-Controlled Induction Study With An Active Treatment Extension To Assess The Efficacy, Safety, And Pharmakokinetics Of Ro7837195 In Patients With Moderately To Severely Active Ulcerative Colitis (GA45977 (SUNCREST))

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Respiratory

A Long-Term Extension Study to Evaluate Safety and Efficacy of Verekitug (UPB-101) in Adult Participants with Severe Asthma who Completed the VALIANT Trial. (UPB-CP-05)

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Cancer and neoplasms

A Phase 1/2, Open-Label, Dose-Escalation, Dose-Expansion Study of Enzomenib (DSP-5336) in Adult Patients with Acute Leukemia and Other Selected Hematologic Malignancies, with and without Mixed Lineage Leukemia (MLL) rearrangement or Nucleophosmin 1 (NPM1) Mutation

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A prospective, real-world registry of acute myeloid leukaemia patients in the United Kingdom

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Cancer and neoplasms

An open-label, multicentre, integrated Phase 1 & 2 study to evaluate the safety, tolerability, radiation dosimetry and anti-tumour activity of Lutetium (177Lu) rhPSMA-10.1 injection in men with metastatic castrate-resistant prostate cancer

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Cancer and neoplasms

A Master Protocol for an Open-Label, Multi-Drug, Multi-Center, Phase II Platform Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Novel Agents or Combinations as Perioperative Treatment in Participants with Locally Advanced Resectable Gastroesophageal Adenocarcinoma (GEMINI-PeriOp GC)

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