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OUH STUDIES

Studies currently being run within Oxford University Hospitals NHS Foundation Trust.

Showing 501 - 510 of 764 studies

Investigating human biology of resident immunity in tissue via neoantigen challenge

Metabolic and Endocrine

A Dose-Escalation Study Evaluating the Safety and Pharmacokinetics of IMC-S118AI in HLA-A*02:01Positive Participants With Type 1 Diabetes (IMC-S118AI-1007)

Musculoskeletal

A Phase 3, Multi centre, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy of a Single Intravenous Dose of SGT-003 in Ambulant Males With Duchenne Muscular Dystrophy (IMPACT DUCHENNE)

Comparative evaluation of sustained meChanical AsPiration Thrombectomy and no thrombus modification for pre-stent thrombus bUrden Reduction in patients with Acute Myocardial Infarction Study: the CAPTURE AMI Study

Cancer and neoplasms

A Phase III, Multicentre, Randomised Controlled Study of Sonesitatug vedotin in Combination with Fluoropyrimidine with or without Rilvegostomig in First-line Claudin18.2-positive, HER2-negative, Advanced/Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (CLARITY-Gastric 02) (D9803C00001 (CLARITY-Gastric 02))

CAPTIVATE - Diet-driven gut microbiome and outcome in patients with early-stage triple-negative breast cancer undergoing neoadjuvant chemotherapy and immunotherapy

Cancer and neoplasms

A Phase III, Randomised, Open-label, Multicentre, Study of Surovatamig as Consolidation Therapy versus Observation after First-line Induction Therapy in Participants with Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma with Unmutated IGHV (SOUNDTRACK-C1)

Musculoskeletal

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Global Study with an Open-Label Extension to Evaluate the Efficacy and Safety of Intravenous AOC 1044 (delpacibart zotadirsen) for the Treatment of DMD with Gene Mutations Amenable to Exon 44 Skipping (SAFARI44)

Neurological

CHTT227A12301: A randomized, placebo-controlled, double-blind Phase 3 study to evaluate the efficacy, safety and tolerability of votoplam in participants with Huntington’s Disease (INVEST HD)

A qualitative study examining patients' experiences with a neurological condition that requires occupational therapy cognitive assessment, exploring different areas of focus across impairment-based and occupation-based screens and assessments