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OUH STUDIES

Studies currently being run within Oxford University Hospitals NHS Foundation Trust.

Showing 571 - 580 of 742 studies

Blood

Expectations, Lived Experience and Views of a Novel FActor Eight (ELEVATE)

Cancer and neoplasms

BNT327-03 – A Phase III, multisite, double-blinded randomized trial of BNT327 in combination with chemotherapy (etoposide/carboplatin) compared to atezolizumab in combination with chemotherapy (etoposide/carboplatin) in participants with first-line extensive-stage small-cell lung cancer (BNT327-03)

A prospective pilot cohort study to investigate the utility and feasibility of using body surface gastric mapping (Gastric Alimetry) to assess gastric motility and function in patients who have undergone elective para-oesophageal hernia repair.

Musculoskeletal

First-in-human study to assess the safety and feasibility of intra-articular administration of allogeneic engineered gingival fibroblasts (aeGF) in participants with knee osteoarthritis (GF-OA-001)

Cancer and neoplasms

A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR-T Cell Therapy, Versus Standard Regimens in Adult Participants with Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

A feasibility study of Remote Patient-Reported Outcome measures in Mitochondrial disease and Spinocerebellar ataxias (R-PROMS)

Cancer and neoplasms

A Phase 1, open-label, multicenter, dose-escalation and cohort expansion study of OKN4395, a dual antagonist of EP2 and EP4 prostanoid receptors, as monotherapy and in combination with pembrolizumab, in patients with advanced solid tumors (INVOKE Trial (OKN-4395-121))

Cancer and neoplasms

A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084 with FOLFOX plus Cetuximab versus FOLFOX with or without Bevacizumab as First-line Treatment of Participants with KRAS G12C Mutant, Metastatic Colorectal Cancer

Cancer and neoplasms

A Phase II/III, multisite, randomized master protocol for a global trial of BNT327 in combination with chemotherapy and other investigational agents in first-line non-small cell lung cancer

Establishment of a research register for patients and families of inherited cardiac condition/cardiomyopathy services (GenetICC)