CHampioning shared decisiOn-making In Craniofacial carE (CHOICE)

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Neurological

A Phase 2, Double-Blind Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of Apitegromab in Subjects <2 Years Old With Spinal Muscular Atrophy (SMA) (OPAL)

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Oral and Gastrointestinal

A Phase IIb, Multicenter, Double-Blind, Placebo-Controlled Induction Study With An Active Treatment Extension To Assess The Efficacy, Safety, And Pharmakokinetics Of Ro7837195 In Patients With Moderately To Severely Active Ulcerative Colitis (GA45977 (SUNCREST))

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Cancer and neoplasms

A Phase 1/2, Open-Label, Dose-Escalation, Dose-Expansion Study of Enzomenib (DSP-5336) in Patients with Acute Leukemia and Other Selected Hematologic Malignancies, with and without Mixed Lineage Leukemia (MLL) rearrangement or Nucleophosmin 1 (NPM1) Mutation

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A prospective, real-world registry of acute myeloid leukaemia patients in the United Kingdom

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Neurological

Long-term extension study to evaluate the safety and efficacy of riliprubart (SAR445088) in participants with chronic inflammatory demyelinating polyneuropathy (CIDP) (Vitalise extension)

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Cancer and neoplasms

An open-label, multicentre, integrated Phase 1 & 2 study to evaluate the safety, tolerability, radiation dosimetry and anti-tumour activity of Lutetium (177Lu) rhPSMA-10.1 injection in men with metastatic castrate-resistant prostate cancer

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Cancer and neoplasms

A Master Protocol for an Open-Label, Multi-Drug, Multi-Center, Phase II Platform Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Novel Agents or Combinations as Perioperative Treatment in Participants with Locally Advanced Resectable Gastroesophageal Adenocarcinoma (GEMINI-PeriOp GC)

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In vivo investigation of immune dynamics following cutaneous challenge (VIVID)

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Safety and Efficacy of Aneurysms Treated with Endovascular Devices (SEATED)

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